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Advanced Epilepsy Surgery in India

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Epilepsy is a condition that can be well controlled in a vast majority of patients. However, 5-10% patients do not achieve adequate seizure control despite trial of best anti-epileptic drug combinations. Such patients are categorized as having refractory or intractable Epilepsy. These patients require special evaluation for treatments other than medical management alone.

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Frequently asked questions about Epilepsy

Q.What is epilepsy surgery?

Epilepsy surgery is a special kind of brain surgery wherein the small part of brain which is responsible for uncontrolled epilepsy can be safely removed without causing any harm.

Q.What can be done for medically refractory epilepsy?
These patients definitely require pre-surgical evaluation for the possibility of surgery to control their seizures.

  • To establish the diagnosis of epileptic seizure
  • Define the kind of epilepsy
  • Define the area of brain responsible for the seizures
  • Evaluate for any abnormal area on special MRI
  • Select ideal surgical candidates with very good correlation
  • Ensure that the surgery will not result in disabling neuro-psychological deficits, by carrying this out at a dedicated Epilepsy Centre.

Q.What is presurgical evaluation?
Pre-surgical evaluation includes Video-EEG monitoring, MRI Brain (epilepsy protocol), PET/SPECT -in selected cases, neuropsychological evaluation and psychiatric evaluation in selected cases. Once the work-up is over, this data is discussed in multidisciplinary patient management conference which includes epileptologist, neurosurgeon, neuro-radiologist , neuro-psychiatrist etc.

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Advanced Surgical Procedures for Management of Epilepsy

Depending on the particular clinical situation, one of the following surgical procedures is chosen by the Medical team at our affiliate hospital. These operations either aim to resect the disease area of the brain, to disconnect it from other areas so as to relieve the seizures, or to lessen their impact.
  1. Anteromedial Temporal Lobectomy
  2. Selective Amygdalohippocampectomy
  3. Electrocorticography guided Resections
  4. Multiple Subpial transections
  5. Quadrantic Resections

6. Multilobar Resections
7. Functional Hemispherotomy
8. Vagal Nerve stimulation
9. Radiosurgery (selected cases)
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Selection of Cases

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Carefully selected patients with intractable epilepsy can have a gratifying outcome in majority of cases. The 2 key points that enable proper selection of cases are:

  • Concordant demonstration of Epileptogenic zone on all the specialized investigations: 3T MRI, PET/SPECT scan, videoEEG, Neuropsychological assessment and clinical evaluation. This means all the tests should point to fits coming from same area of the brain.

  • Can the area of origin of fits be operated safely without producing deficit. This has to be judged by a surgeon experienced with such procedures.

Once the above two conditions are met, the patient can be further counselled and likely outcome explained keeping in mind the specific situation. For example, surgery for seizure focus in temporal lobe of the brain has a better outcome than other areas. Similarly, cases wherein MRI shows abnormal area have greater chances of success ** PLEASE DESCRIBE THIS IMAGE **than those in which MRI is completely normal.

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